martes, 2 de noviembre de 2010

ARANDANOS - Osteoporosis Pos-menopáusica

¿Sabía que el consumo de arándanos puede evitar la osteoporosis pos-menopáusica?


Aquí le presentamos el resumen de un estudio realizado sobre la relación entre arándanos y osteoporosis en ratas ovariectomizadas. La conclusión es la siguiente: "In summary, our findings indicate that blueberry can prevent bone loss as seen by the increases in BMD and favorable changes in biomarkers of bone metabolism".

Resumen
The objective of the present study was to explore the bone protective role of blueberry in an ovariectomized rat model. Thirty 6-month-old female Sprague–Dawley rats were either sham-operated (Sham) or ovariectomized (Ovx) and divided into three groups: Sham, Ovx (control), Ovx+blueberry (5% blueberry w/w). After 100 days of treatment, rats were euthanized, and blood and tissues were collected. Bone mineral
density (BMD) and content of whole body, right tibia, right femur and fourth lumbar vertebra were assessed via dual-energy X-ray absorptiometry. As expected, Ovx resulted in loss of whole-body, tibial, femoral, and 4th lumbar BMD by approximately 6%. Blueberry treatment was able to prevent the loss of whole-body BMD and had an intermediary effect on prevention of tibial and femoral BMD when compared to either Sham or Ovx controls. The bone-protective effects of blueberry may be due to suppression of Ovx-induced increase in bone turnover, as evident by lowered femoral mRNA levels of alkaline phosphatase, collagen type I and tartrate-resistant acid phosphatase to the Sham levels. Similarly, serum osteocalcein levels were also lower in the blueberry group when compared to the Ovx control group, albeit not significantly. In summary, our findings indicate that blueberry can prevent bone loss as seen by the increases in BMD and favorable changes in biomarkers of bone metabolism.

Fuente: Latha Devareddya et al., Blueberry prevents bone loss in ovariectomized rat model of postmenopausal osteoporosis, Journal of Nutritional Biochemistry 19 (2008) 694–699.

Nota:
Una copia de este artículo se puede solicitar a LIOFRUT@gmail.com

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